Karen E Chapman Selected Research

11-beta-Hydroxysteroid Dehydrogenases (11beta Hydroxysteroid Dehydrogenase)

12/2011	Expression of 11beta-hydroxysteroid dehydrogenase 2 contributes to glucocorticoid resistance in lymphoblastic leukemia cells.
5/2007	Omental 11beta-hydroxysteroid dehydrogenase 1 correlates with fat cell size independently of obesity.
3/2006	11Beta-hydroxysteroid dehydrogenase type 1--a role in inflammation?
1/2006	Polymorphisms in the gene encoding 11B-hydroxysteroid dehydrogenase type 1 (HSD11B1) and lifetime cognitive change.

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Karen E Chapman Research Topics

Disease

18	Inflammation (Inflammations) 09/2020 - 03/2006
10	Obesity 09/2020 - 01/2004
8	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2014 - 01/2004
5	Hypertension (High Blood Pressure) 11/2020 - 08/2003
4	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2020 - 12/2009
4	Heart Failure 01/2019 - 01/2016
4	Metabolic Diseases (Metabolic Disease) 06/2011 - 05/2007
3	Premature Birth (Birth, Premature) 11/2021 - 04/2014
3	Infections 10/2018 - 03/2008
3	Hypertrophy 01/2017 - 05/2007
3	Rheumatoid Arthritis 09/2013 - 11/2006
3	Atherosclerosis 05/2013 - 12/2008
3	Insulin Resistance 06/2011 - 05/2002
2	Cardiovascular Diseases (Cardiovascular Disease) 11/2020 - 01/2018
2	Fibrosis (Cirrhosis) 01/2018 - 01/2017
2	Glucocorticoid Receptor Deficiency 01/2018 - 12/2011
2	Myocardial Infarction 01/2017 - 01/2016
2	Type 2 Diabetes Mellitus (MODY) 04/2012 - 01/2010
2	Abdominal Obesity 06/2011 - 04/2011
2	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 06/2008 - 06/2004
1	COVID-19 11/2020
1	Critical Illness (Critically Ill) 11/2020
1	Mental Disorders (Mental Disorder) 09/2020
1	Mucocutaneous Lymph Node Syndrome (Kawasaki Disease) 11/2019
1	Parasitemia 10/2018
1	Malaria 10/2018
1	Hypoglycemia (Reactive Hypoglycemia) 10/2018
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2018
1	Cognitive Dysfunction 01/2018
1	Arthritis (Polyarthritis) 09/2017
1	Vascular Calcification 11/2016
1	Immune System Diseases (Immune Disorders) 11/2016
1	Fetal Growth Retardation (Intrauterine Growth Retardation) 05/2016
1	Fetal Weight 05/2016
1	Pulmonary Edema 01/2016
1	Infarction (Infarctions) 01/2016
1	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2016
1	Heart Diseases (Heart Disease) 01/2016
1	Neoplasms (Cancer) 04/2015
1	Disease Susceptibility (Diathesis) 05/2014
1	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (Leukemia, Pre B Cell) 05/2014
1	Simpson-Golabi-Behmel syndrome 01/2014
1	Vascular System Injuries 05/2013
1	Muscle Weakness 01/2013
1	Sarcopenia 01/2013
1	Atrophy 01/2013

Drug/Important Bio-Agent (IBA)

32	GlucocorticoidsIBA 11/2021 - 11/2006
15	Oxidoreductases (Dehydrogenase)IBA 09/2020 - 11/2006
11	EnzymesIBA 09/2020 - 06/2005
10	11-beta-Hydroxysteroid Dehydrogenase Type 1IBA 01/2013 - 01/2004
8	Messenger RNA (mRNA)IBA 09/2017 - 05/2004
6	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 11/2021 - 05/2002
5	CorticosteroneIBA 01/2017 - 05/2004
4	CytokinesIBA 10/2018 - 04/2012
4	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2013 - 01/2004
4	11-beta-Hydroxysteroid Dehydrogenases (11beta Hydroxysteroid Dehydrogenase)IBA 12/2011 - 01/2006
3	Adrenal Cortex Hormones (Corticosteroids)IBA 11/2021 - 01/2017
3	SteroidsIBA 11/2020 - 05/2010
3	Hormones (Hormone)IBA 11/2020 - 03/2009
3	Dexamethasone (Maxidex)FDA LinkGeneric 11/2020 - 12/2009
3	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 01/2019 - 01/2016
2	Myosin Heavy Chains (Myosin Heavy Chain)IBA 01/2017 - 01/2016
2	Cortisone FDA Link 09/2013 - 03/2009
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 11/2020
1	Angiotensin Receptor AntagonistsIBA 11/2020
1	Mineralocorticoid Receptor AntagonistsIBA 11/2020
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	Glucose (Dextrose)FDA LinkGeneric 10/2018
1	Liver GlycogenIBA 10/2018
1	Insulin (Novolin)FDA Link 10/2018
1	SaltsIBA 01/2018
1	Carbon Tetrachloride (Tetrachloromethane)IBA 01/2018
1	SodiumIBA 01/2018
1	(4- (2- chlorophenyl- 4- fluoro- 1- piperidinyl)(5- (1H- pyrazol- 4- yl)- 3- thienyl)methanoneIBA 01/2018
1	LipopolysaccharidesIBA 01/2018
1	Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)IBA 01/2018
1	AlbuminsIBA 01/2018
1	11-dehydrocorticosteroneIBA 01/2017
1	Proteins (Proteins, Gene)FDA Link 01/2017
1	Spironolactone (Aldactone)FDA LinkGeneric 01/2017
1	Chemotactic FactorsIBA 01/2017
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2016
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 05/2016
1	Pravastatin (Pravachol)FDA LinkGeneric 05/2016
1	AldosteroneIBA 01/2016
1	Atrial Natriuretic Factor (ANF)IBA 01/2016
1	Interleukin-15 (Interleukin 15)IBA 05/2014
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2014
1	Metformin (Glucophage)FDA LinkGeneric 01/2014
1	IsoenzymesIBA 05/2013
1	LipidsIBA 05/2013
1	Apolipoproteins E (ApoE)IBA 04/2013
1	ApolipoproteinsIBA 04/2013
1	SalicylatesIBA 04/2012
1	CarrageenanIBA 01/2012

Therapy/Procedure

6	Therapeutics 11/2020 - 06/2006
2	Glycemic Control 05/2013 - 04/2012
1	Adrenalectomy 10/2018
1	Intraperitoneal Injections 01/2018
1	Transplantation 04/2013